ChromaNik Technologies Inc.

Specialist manufacturer of columns, the essential component for liquid separation and analysis equipment

ChromaNik Technologies is a specialist manufacturer of columns, an essential component in high-performance liquid chromatography (HPLC) systems used to separate and analyse components in liquids.
Columns are critically important components that determine the separation performance and efficiency of sample constituents. Their development demands high technical expertise to ensure durability and reliability while incorporating ever-evolving technologies.
The company possesses numerous proprietary technologies for the chemical modification of silica gel, the packing material within the columns, supporting research across diverse fields including pharmaceuticals, food, and the environment.

The company develops its own fillers and continues to refine them.

The company's development efforts are rooted in the chemical exploration of ‘how to reactively approach and promote deactivation’ on highly active surfaces such as silica. Leveraging its strength in in-house filler development, it has created numerous column products offering extended longevity and excellent reproducibility for reverse-phase HPLC analysis used in pharmaceuticals, food, and environmental sectors.
The foundational technologies developed and refined in-house to date are extensive.Examples include surface porous (core-shell) particles that suppress sample diffusion to achieve high separation efficiency at low pressure; silanol activity control (SAC); advanced end-capping methods (Sunniest EC, Tandem TMS); organically inert components (Prominert Surface); and innovative organic silica combined with advanced surface treatment (Ultra Hybrid Technology).
Furthermore, through the introduction of new external technologies and collaborative research with analytical institutions, we are actively engaged in developing novel HPLC columns.

Strengths

The first column to adopt core-shell particles was the “SunShell” series launched in 2011. This column combined core-shell particles—then the latest technology offering high performance at low pressure—with the company's foundational silica surface deactivation method, resulting in a “highly inert core-shell column”.
Boasting a significantly longer service life than comparable competitor products, it remains a popular item, currently accounting for over 50% of the company's sales. This deactivation technology was recognised as the sixth item in the Liquid Chromatography Scientific Heritage series in 2023.

The Ultra Hybrid Column “SunBridge” series launched by them in 2025 demonstrates chemical stability even under high-load conditions where conventional columns degrade prematurely. This is evidenced by its high resistance in both pH 1 acid durability testing and pH 11.5 alkaline durability testing.
Generally, materials created by processing organic compounds such as ethylene onto inorganic silica are collectively termed hybrid silica; however, in reality, surface modification constitutes the majority of such approaches. ‘SunBridge’ achieves extraordinary performance by utilising its proprietary ethylene-crosslinked silica gel to deactivate both the inner and outer surfaces.

Message from President

ChromaNik Technologies is a specialist HPLC column manufacturer whose mission is to ‘support analytical reliability with proven technology’ based on chemistry. We have earnestly addressed analytical challenges and pursued the development of high-quality packing materials and columns through various technological innovations. Moving forward, we remain committed to maintaining quality and continuous improvement, continuing to produce columns that meet and exceed expectations.

Major Equipment

• High-Performance Liquid ChromatographyProminence LC-20A Series, etc.
  Shimadzu Corporation, etc.10 units

Company Overview

Company Name

ChromaNik Technologies Inc.

Address

3rd Floor, Tomoe Building, 6-3-1 Namikodome, Minato-ku, Osaka

Company President

CEO Norikazu Nagae

Founded / Established

December.2005/December.2005

Number of Employees

9　

Phone

06-6581-0885

Fax

06-6581-0890

E-mail

info@chromanik.co.jp

Official Website

https://chromanik.co.jp/en/

Capital

49,500K JPY